Regio- and Stereoselective Synthesis of C-4′ Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues-Reference-Cited by-同舟云学术

Regio- and Stereoselective Synthesis of C-4′ Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues

Published:2021-11-03 Issue:22 Volume:23 Page:8828-8833
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Jouffroy Lucile¹^ORCID,Verhoeven Jonas²³,Brambilla Marta²,Verniest Guido²³,Kong Hanchu⁴,Zhao Yongbin⁴,Wang Wenbin⁴,Meerpoel Lieven²,Thuring Jan Willem²^ORCID,Winne Johan M.¹^ORCID

Affiliation:

1. Department of Organic and Macromolecular Chemistry, Ghent University, Campus Sterre, Krijgslaan 281-S4, 9000 Gent, Belgium

2. Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340 Beerse, Belgium

3. Research Group of Organic Chemistry (ORGC), Department of Chemistry and Department of Bio-engineering Sciences, Faculty of Science and Bio-engineering Sciences, Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium

4. Department of Synthetic Chemistry, Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, People’s Republic of China

Funder

Agentschap Innoveren en Ondernemen

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.1c03334

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1. Adenine Arabinoside Therapy of Herpes Zoster in the Immunosuppressed

2. Treatment of herpes simplex virus infections