Modular Total Syntheses of the Alkaloids Discoipyrroles A and B, Potent Inhibitors of the DDR2 Signaling Pathway
Author:
Affiliation:
1. Research School of Chemistry, Institute of Advanced Studies, The Australian National University, Canberra, ACT 2601, Australia
Funder
Australian Research Council
China Scholarship Council
Institute of Advanced Studies, Australian National University
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.5b03672
Reference29 articles.
1. Discoipyrroles A–D: Isolation, Structure Determination, and Synthesis of Potent Migration Inhibitors from Bacillus hunanensis
2. Using Functional Signature Ontology (FUSION) to Identify Mechanisms of Action for Natural Products
3. Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma
4. The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis
5. DDR2 inhibition reduces migration and invasion of murine metastatic melanoma cells by suppressing MMP2/9 expression through ERK/NF- B pathway
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