Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction-Reference-Cited by-同舟云学术

Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction

Published:2022-10-20 Issue:43 Volume:24 Page:7924-7927
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Hassell-Hart Storm¹,Speranzini Elisa¹,Srikwanjai Sirihathai¹,Hossack Euan²,Roe S. Mark²,Fearon Daren³^ORCID,Akinbosede Daniel²,Hare Stephen²,Spencer John¹^ORCID

Affiliation:

1. Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, U.K.

2. Department of Biochemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QG, U.K.

3. Diamond LightSource (DLS), Harwell Science and Innovation Campus, Didcot OX11 0DE, U.K.

Funder

Engineering and Physical Sciences Research Council

Royal Thai Government

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c02996

Reference35 articles.

1. Synthesis and biological activity of natural thiazoles: An important class of heterocyclic compounds

2. A Hantzsch synthesis of 2-aminothiazoles performed in a heated microreactor system

3. A structure–activity relationship study on multi-heterocyclic molecules: two linked thiazoles are required for cytotoxic activity

4. Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery

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