Total Synthesis of Resiniferatoxin Enabled by Photocatalytic Decarboxylative Radical Cyclization
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Funder
Ministry of Education, Culture, Sports, Science and Technology
Japan Society for the Promotion of Science
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.1c04286
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3. Plant Orthoesters
4. Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper
5. Resiniferatoxin: The Evolution of the “Molecular Scalpel” for Chronic Pain Relief
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