A Versatile Synthesis of Vinyl-Substituted Heterocycles via Regio- and Enantioselective Pd-Catalyzed Tandem Allylic Substitution

Author:

Qian Chao1,Tang Wenjun12ORCID

Affiliation:

1. State Key Laboratory of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, 345 Ling Ling Road, Shanghai 200032, China

2. School of Chemistry and Material Science, University of Chinese Academy of Sciences, 1 Sub-lane Xiangshan, Hangzhou 310024, China

Funder

K. C. Wong Education Foundation

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference46 articles.

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2. Synthesis and evaluation of conformationally restricted N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at .sigma. receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds

3. Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

4. Aicher, T. D.; Chen, Z. D.; Le, H. Y.; Martin, F. M.; Pineiro-Nunez, M. M.; Rocco, V. P.; Ruley, K. M.; Shaus, J. M.; Spinazze, P. G.; Tupper, D. E. Piperazine substituted aryl benzodiazepines. WO 2004/014895, 2004.

5. Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists

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