Access to Piperazine-Fused Pyrrolocarbazoles Enabled by Acid-Catalyzed Stereoselective Hydroarylation of Ynamide–Indoles and Subsequent Diels–Alder Reactions/Aromatizations-Reference-Cited by-同舟云学术

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Access to Piperazine-Fused Pyrrolocarbazoles Enabled by Acid-Catalyzed Stereoselective Hydroarylation of Ynamide–Indoles and Subsequent Diels–Alder Reactions/Aromatizations

Published:2024-08-12 Issue:35 Volume:26 Page:7273-7278
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zhou Ze¹,Huang Xiang¹,Wei Qing-Yi¹,Wang Yi-Lin¹,Wu Bin¹,Yang Jin-Ming¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, People’s Republic of China

Funder

South-Central University for Nationalities

Natural Science Foundation of Hubei Province

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c01889

Reference53 articles.

1. Targeting WEE1 Kinase in Cancer

2. Structure-activity relationships of Wee1 inhibitors: A review

3. Synthetic and Medicinal Chemistry Approaches Toward WEE1 Kinase Inhibitors and Its Degraders

4. 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitution

5. Synthesis and structure–activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases

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