Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED-Reference-Cited by-同舟云学术

Structural Elucidation and Absolute Stereochemistry for Pharma Compounds Using MicroED

Published:2024-08-08 Issue:33 Volume:26 Page:6944-6949
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

de Moraes Lygia Silva¹,Burch Jessica E.¹²³,Delgadillo David A.¹^ORCID,Rodriguez Isabel Hernandez¹,Mai Huanghao¹^ORCID,Smith Austin G.⁴,Caille Seb⁴^ORCID,Walker Shawn D.⁴,Wurz Ryan P.⁵^ORCID,Cee Victor J.⁵,Rodriguez Jose A.²^ORCID,Gostovic Dan³,Quasdorf Kyle⁴^ORCID,Nelson Hosea M.¹²^ORCID

Affiliation:

1. Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States

2. Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States

3. MicroEDLab.com, 1623 Central Avenue Suite 18, Cheyenne, Wyoming 82001, United States

4. Drug Substance Technologies - Synthetics, Process Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States

5. Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States

Funder

National Science Foundation Graduate Research Fellowship Program

Division of Graduate Education

David and Lucile Packard Foundation

Amgen

Arnold and Mabel Beckman Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c01865

Reference25 articles.

1. NMR crystallography of molecular organics

2. X‐Ray Analysis and the Structure of Organic Molecules

3. The use of X-ray crystallography to determine absolute configuration

4. The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination

5. Microcrystal electron diffraction in macromolecular and pharmaceutical structure determination