Synthesis of N-Glyoxylyl Peptides Enabled by a Lossen Rearrangement-Induced Intramolecular Redox Reaction of N-Terminal Glycyl Hydroxamic Acid
Author:
Affiliation:
1. Institute of Biomedical Sciences and Graduate School of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan
2. Faculty of Pharmaceutical Sciences, Tokushima University, Tokushima 770-8505, Japan
Funder
Canon Foundation for Scientific Research
Japan Society for the Promotion of Science
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c01126
Reference34 articles.
1. α-Oxo Aldehyde or Glyoxylyl Group Chemistry in Peptide Bioconjugation
2. Preparation of protein conjugates via intermolecular hydrazone linkage
3. Unprotected Peptides as Building Blocks for the Synthesis of Peptide Dendrimers with Oxime, Hydrazone, and Thiazolidine Linkages
4. Nucleophilic Catalysis of Hydrazone Formation and Transimination: Implications for Dynamic Covalent Chemistry
5. Fluorescence Probe with a pH-Sensitive Trigger
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1. Late-Stage Formation of a Sactionine Linkage Enabled by Lossen Rearrangement of Glycyl Hydroxamic Acid;Organic Letters;2024-06-07
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