Indolyl-based Copper(I) Complex-Catalyzed Intermolecular Trifluoromethylazolation of Alkenes via Radical Process

Author:

Yuan Qingbing1,Huang Zeming2,Chai Zhuo1ORCID,Hong Dongjing1,Zhu Shan1,Zhou Shuangliu1ORCID,Zhu Xiancui1ORCID,Wei Yun1,Wang Shaowu123ORCID

Affiliation:

1. Key Laboratory of Functionalized Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241000, China

2. Anhui Laboratory of Functional Complexes for Materials Chemistry and Application, College of Chemical and Environmental Engineering, Anhui Polytechnic University, Wuhu, Anhui 241000, China

3. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Funder

Anhui Normal University

Anhui Department of Education

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference55 articles.

1. aAli, A.; Aster, S. D.; Balkovec, J. M.; Graham, D. W.; Hunt, J. A.; Kallashi, F.; Sinclair, P. J.; Tata, J. R.; Taylor, G. E.; Goulet, J. L. Preparation of octahydro-2-H-naphtho[1,2-F]indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators for the treatment of autoimmune and inflammatory conditions. WO 2004026248 A2 20040401.

2. bPilkington, B. L.; Armstrong, S.; Barnes, N. J.; Barnett, S. P.; Clarke, E. D.; Crowley, P. J.; Fraser, T. E. M.; Hughes, D. J.; Mathews, C. J.; Salmon, R.; Smith, S. C.; Viner, R.; Whittingham, W. G.; Williams, J.; Whittle, A. J.; Mound, W. R.; Urch, C. J. Preparation of benzazoles as fungicides, insecticides, acaricides, molluscicides, and nematocides. WO Patent WO 2001055145 A1 20010802.

3. cPeters, K. G.; Shalwitz, R. N-Arylsulfamic acid derivatives as HPTP-β inhibitors and their preparation and use for treatment of ocular edema, neovascularization and related diseases. WO Patent WO 2012047966 A2 20120412.

4. dKelley, R.; Li, H.; Heckrodt, T.; Chen, Y.; McMurtrie, D.; Tso, K.; Taylor, V.; Singh, R.; Yen, R.; Maung, J. Preparation of pyrazole derivatives as IRAK kinase inhibitors useful in treatment and prevention of IRAK-assocd Diseases. WO Patent WO 2016172560 A1 20161027.

5. Metal-catalyzed asymmetric heteroarylation of alkenes: diverse activation mechanisms

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