Highly Stereodivergent Construction of a C2-Symmetric cis,cis- and trans,trans-2,6-Dioxabicyclo[3.3.0]octane Framework by Double Intramolecular Amide Enolate Alkylation: Total Synthesis of (+)-Laurenidificin and (+)-Aplysiallene-Reference-Cited by-同舟云学术

Highly Stereodivergent Construction of a C₂-Symmetric cis,cis- and trans,trans-2,6-Dioxabicyclo[3.3.0]octane Framework by Double Intramolecular Amide Enolate Alkylation: Total Synthesis of (+)-Laurenidificin and (+)-Aplysiallene

Published:2022-11-30 Issue:48 Volume:24 Page:8780-8785
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Shin Iljin¹^ORCID,Jang Hongjun¹,Kwak Soo Yeon¹,Park Youngjik¹^ORCID,Lee Dongjoo¹^ORCID,Kim Hyoungsu¹^ORCID,Kim Deukjoon²^ORCID

Affiliation:

1. College of Pharmacy and Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Suwon 16499, Korea

2. The Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea

Funder

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c03494

Reference32 articles.

1. Halogenated Organic Molecules of Rhodomelaceae Origin: Chemistry and Biology

2. KUMAUSALLENE, A NEW BROMOALLENE FROM THE MARINE RED ALGALAURENCIA NIPPONICAYAMADA

3. General approach to halogenated tetrahydrofuran natural products from red algae of the genus Laurencia. Total synthesis of (.+-.)-kumausallene and (.+-.)-1-epi-kumausallene

4. Enantioselective Total Synthesis of the Nonisoprenoid Sesquiterpene (−)-Kumausallene

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