Asymmetric Total Synthesis and Biological Evaluation of the Natural PDE4 Inhibitor Toddacoumalone-Reference-Cited by-同舟云学术

Asymmetric Total Synthesis and Biological Evaluation of the Natural PDE4 Inhibitor Toddacoumalone

Published:2020-01-06 Issue:2 Volume:22 Page:584-588
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Hou Ke-Qiang¹,Chen Xue-Ping¹,Huang Yiyou¹,Chan Albert S. C.¹^ORCID,Luo Hai-Bin¹^ORCID,Xiong Xiao-Feng¹^ORCID

Affiliation:

1. Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China

Funder

National Natural Science Foundation of China

Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery

Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme

Guangdong Natural Science Funds for Distinguished Young Scholar

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.9b04355

Reference47 articles.

1. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

2. Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

3. Roflumilast

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