A Scalable Synthesis of the Blue Fluorescent Amino Acid 4-Cyanotryptophan and the Fmoc Derivative: Utility Demonstrated with the Influenza M2 Peptide Tetramer-Reference-Cited by-同舟云学术

A Scalable Synthesis of the Blue Fluorescent Amino Acid 4-Cyanotryptophan and the Fmoc Derivative: Utility Demonstrated with the Influenza M2 Peptide Tetramer

Published:2021-02-03 Issue:4 Volume:23 Page:1247-1250
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Micikas Robert¹,Acharyya Arusha¹,Gai Feng¹^ORCID,Smith Amos B.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Pennsylvania, 231 South 34th St, Philadelphia, Pennsylvania 19104, United States

Funder

NSF MRSEC program at the University of Pennsylvania

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c04055

Reference26 articles.

1. Blue fluorescent amino acid for biological spectroscopy and microscopy

2. Systematic Evaluation of Soluble Protein Expression Using a Fluorescent Unnatural Amino Acid Reveals No Reliable Predictors of Tolerability

3. A Strategic Approach for Fluorescence Imaging of Membrane Proteins in a Native-like Environment

4. The Kinetic and Molecular Basis for the Interaction of LexA and Activated RecA Revealed by a Fluorescent Amino Acid Probe

5. Cyano-tryptophans as dual infrared and fluorescence spectroscopic labels to assess structural dynamics in proteins

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