Simultaneous Construction of C–N Axial and Central Chirality via Silver-Catalyzed Desymmetrizative [3 + 2] Cycloaddition of Prochiral N-Aryl Maleimides with Activated Isocyanides-Reference-Cited by-同舟云学术

Simultaneous Construction of C–N Axial and Central Chirality via Silver-Catalyzed Desymmetrizative [3 + 2] Cycloaddition of Prochiral N-Aryl Maleimides with Activated Isocyanides

Published:2022-06-20 Issue:25 Volume:24 Page:4645-4649
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zhang Sen¹,Luo Zhang-Hong¹,Wang Wen-Tao¹,Qian Linghui¹^ORCID,Liao Jia-Yu¹²^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, and Hangzhou Institute of Innovative Medicine, Zhejiang University, Hangzhou, China, 310058

2. Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, China, 310018

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c01761

Reference46 articles.

1. The Challenge of Atropisomerism in Drug Discovery

2. A twist of nature – the significance of atropisomers in biological systems

3. Atropisomerism in medicinal chemistry: challenges and opportunities

4. Atroposelective transformation of axially chiral (hetero)biaryls. From desymmetrization to modern resolution strategies

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