Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives-Reference-Cited by-同舟云学术

Divergent Synthesis and Real-Time Biological Annotation of Optically Active Tetrahydrocyclopenta[c]pyranone Derivatives

Published:2016-12-07 Issue:24 Volume:18 Page:6280-6283
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Nelson Shawn D.¹²,Wawer Mathias J.¹²,Schreiber Stuart L.¹²^ORCID

Affiliation:

1. Howard Hughes Medical Institute and Center for the Science of Therapeutics, The Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, Massachusetts 02142, United States

2. Department of Chemistry & Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

Funder

Harvard University

National Institute of General Medical Sciences

Eli Lilly and Company

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.6b03118

Reference34 articles.

1. Scaffold composition and biological relevance of screening libraries

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4. Dark chemical matter as a promising starting point for drug lead discovery

5. Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

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