Monoterpene Indole Alkaloid-Like Compounds Based on Diversity-Enhanced Extracts of Iridoid-Containing Plants and Their Immune Checkpoint Inhibitory Activity
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aza-Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan
2. Research and Development Center, FUSO Pharmaceutical Industries, LTD., 2-3-30 Morinomiya, Joto-ku, Osaka 536-8523, Japan
Funder
Takeda Science Foundation
Ministry of Education, Culture, Sports, Science, and Technology
Japan Agency for Medical Research and Development
Kobayashi International Scholarship Foundation
Shorai Foundation for Science and Technology
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.6b03057
Reference41 articles.
1. Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2. Chemical Diversity of Natural Resources and the Bioactivity of their Constituents
3. Development of Diversity-Enhanced Extracts of Curcuma zedoaria and Their New Sesquiterpene-like Compounds
4. Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
5. Generating Diverse Skeletons of Small Molecules Combinatorially
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