Targeted Discovery and Combinatorial Biosynthesis of Polycyclic Tetramate Macrolactam Combamides A

Targeted Discovery and Combinatorial Biosynthesis of Polycyclic Tetramate Macrolactam Combamides A–E

Published:2018-05-24 Issue:12 Volume:20 Page:3504-3508
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Liu Yan¹,Wang Haoxin²,Song Rentai²,Chen Jining¹,Li Tianhong¹,Li Yaoyao¹^ORCID,Du Liangcheng²³^ORCID,Shen Yuemao¹²^ORCID

Affiliation:

1. Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong 250012, P. R. China

2. State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, P. R. China

3. Department of Chemistry, University of Nebraska Lincoln, Lincoln, Nebraska 68588, United States

Funder

Ministry of Education of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b01285

Reference23 articles.

1. Structure and Biosynthesis of Heat-Stable Antifungal Factor (HSAF), a Broad-Spectrum Antimycotic with a Novel Mode of Action

2. Geodin A Magnesium Salt: A Novel Nematocide from a Southern Australian Marine Sponge, Geodia

3. Cylindramide: Cytotoxic tetramic acid lactam from the marine sponge Halichondria cylindrata Tanita & Hoshino

4. A NEW ANTIBIOTIC, IKARUGAMYCIN

5. ABURATUBOLACTAM A, A NOVEL INHIBITOR OF SUPEROXIDE ANION GENERATION FROM A MARINE MICROORGANISM

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Critical analysis of polycyclic tetramate macrolactam biosynthetic gene cluster phylogeny and functional diversity;Applied and Environmental Microbiology;2024-06-18

2. Discovery of Aburatubolactams Reveals Biosynthetic Logic for Distinct 5/5-Type Polycyclic Tetramate Macrolactams;Organic Letters;2024-02-16

3. Critical analysis of polycyclic tetramate macrolactam biosynthetic cluster phylogeny and functional diversity;2024-01-23

4. A Mechanistic Understanding of the Distinct Regio‐ and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates;Angewandte Chemie International Edition;2023-11-14

5. A Mechanistic Understanding of the Distinct Regio‐ and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates;Angewandte Chemie;2023-11-14