Cytochrome P450 Monooxygenase for Catalyzing C-42 Hydroxylation of the Glycine-Derived Fragment in Hangtaimycin Biosynthesis-Reference-Cited by-同舟云学术

Cytochrome P450 Monooxygenase for Catalyzing C-42 Hydroxylation of the Glycine-Derived Fragment in Hangtaimycin Biosynthesis

Published:2022-02-09 Issue:6 Volume:24 Page:1388-1393
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Li Xingxing¹²,Fu Jie¹²,Li Yihua¹,Liu Jiachang¹²,Gao Rongmei¹,Shi Yuanyuan¹²,Li Yihong¹²,Sun Hongmin¹²,Wang Lifei¹²,Li Yuhuan¹,Jiang Bingya¹²^ORCID,Wu Linzhuan¹²,Hong Bin¹²^ORCID

Affiliation:

1. NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Tiantan Xili, 100050 Beijing, China

2. CAMS Key Laboratory of Synthetic Biology for Drug Innovation, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Tiantan Xili, 100050 Beijing, China

Funder

Chinese Academy of Medical Sciences

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.2c00242

Reference31 articles.

1. Hangtaimycin, a peptide secondary metabolite discovered from Streptomyces spectabilis CPCC 200148 by chemical screening

2. The Mechanism of Dehydrating Bimodules in trans ‐Acyltransferase Polyketide Biosynthesis: A Showcase Study on Hepatoprotective Hangtaimycin