Synthesis of Chiral Cyclic Alcohols from Chiral Epoxides by H or N Substitution with Frontside Displacement
Author:
Affiliation:
1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States
Funder
Pfizer
Bristol-Myers Squibb
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b02822
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1. Simple Enantioselective Syntheses of (2R,6R)-Hydroxynorketamine and Related Potential Rapid-Onset Antidepressants
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3. Highly Enantioselective, Catalytic Epoxidation of Trisubstituted Olefins
4. Asymmetric Epoxidation of trans-β-Methylstyrene and 1-Phenylcyclohexene Using aD-Fructose-Derived Ketone: (R,R)-trans-β-Methylstyrene Oxide and (R,R)-1-Phenylcyclohexene Oxide
5. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression
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