Total Synthesis of the 2,5-Disubstituted γ-Pyrone E1 UAE Inhibitor Himeic Acid A-Reference-Cited by-同舟云学术

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Total Synthesis of the 2,5-Disubstituted γ-Pyrone E1 UAE Inhibitor Himeic Acid A

Published:2023-10-06 Issue:41 Volume:25 Page:7502-7506
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Lu Heyuan¹,Handore Kishor L.¹^ORCID,Wood Tabitha E.¹²^ORCID,Shimokura Grace K.¹^ORCID,Schimmer Aaron D.²,Batey Robert A.¹³^ORCID

Affiliation:

1. Davenport Research Laboratories, Dept. of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada

2. Princess Margaret Cancer Centre, University Health Network, 101 College Street, Toronto, ON M5G 1L7, Canada

3. Acceleration Consortium, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada

Funder

Canadian Institutes of Health Research

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c02761

Reference41 articles.

1. Small-Molecule Modulation of Protein Homeostasis

2. Non-peptidic natural products as ubiquitin-proteasome inhibitors

3. E1 Enzymes as Therapeutic Targets in Cancer

4. Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation

5. Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine Cyanobacterium Symploca sp.

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1. The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening;Scientific Data;2024-06-06

2. 4-Hydroxy-2-pyrones: Synthesis, Natural Products, and Application;Organics;2023-12-15

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