Synthesis of CHF<sub>2</sub>-Containing Heterocycles through Oxy-difluoromethylation Using Low-Cost 3D Printed PhotoFlow Reactors-Reference-Cited by-同舟云学术

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Synthesis of CHF₂-Containing Heterocycles through Oxy-difluoromethylation Using Low-Cost 3D Printed PhotoFlow Reactors

Published:2024-01-08 Issue:14 Volume:26 Page:2877-2882
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zhang Jinlei¹,Selmi-Higashi Elias¹,Zhang Shen¹²,Jean Alexandre³,Hilton Stephen T.⁴^ORCID,Cambeiro Xacobe C.²^ORCID,Arseniyadis Stellios¹^ORCID

Affiliation:

1. Department of Chemistry, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom

2. School of Science, University of Greenwich, Central Avenue, Gillingham ME4 4TB, United Kingdom

3. Industrial Research Centre, Oril Industrie, 13 rue Desgenétais, Bolbec 76210, France

4. UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, United Kingdom

Funder

Engineering and Physical Sciences Research Council

Royal Society

Queen Mary University of London

China Scholarship Council

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c03997

Reference36 articles.

1. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

2. Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

3. Where Does the Fluorine Come From? A Review on the Challenges Associated with the Synthesis of Organofluorine Compounds

4. Fluorine in Pharmaceuticals: Looking Beyond Intuition

5. Late-stage C–H functionalization offers new opportunities in drug discovery

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Visible Light-Induced Radical Cascade Difluoromethylation/Cyclization of Unactivated Alkenes: Access to CF₂H-Substituted Polycyclic Imidazoles;ACS Omega;2024-06-19

2. Recent advances in 3D printing for continuous flow chemistry;Current Opinion in Green and Sustainable Chemistry;2024-06

3. Visible light-mediated difluoromethylation/cyclization in batch and flow: scalable synthesis of CHF₂-containing benzimidazo- and indolo[2,1-a]isoquinolin-6(5H)-ones;Chemical Communications;2024

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