Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials-Reference-Cited by-同舟云学术

Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials

Published:2024-01-22 Issue:14 Volume:26 Page:2837-2842
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Kaburagi Yosuke¹^ORCID,Kira Kazunobu¹,Yahata Kenzo²^ORCID,Iso Kentaro¹,Sato Yuki¹,Matsuura Fumiyoshi¹,Ohashi Isao¹,Matsumoto Yasunobu¹,Isomura Minetaka¹^ORCID,Sasaki Takeo¹,Fukuyama Takashi¹,Miyashita Yusuke³,Azuma Hiroshi¹,Iida Daisuke¹,Ishida Tasuku¹^ORCID,Itano Wataru¹,Matsuda Masaaki¹,Matsukura Masayuki¹,Murai Norio¹,Nagao Satoshi¹,Seki Masashi¹,Yamamoto Akihiko¹,Yamamoto Yuji¹,Yoneda Naoki¹,Watanabe Yuzo³,Kamada Atsushi¹,Kayano Akio³,Tagami Katsuya¹,Asano Osamu¹,Owa Takashi¹,Kishi Yoshito²^ORCID

Affiliation:

1. Tsukuba Research Laboratories, Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan

2. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

3. Kashima Plant, Eisai Co., Ltd., 22 Sunayama, Kamisu-shi, Ibaraki 314-0255, Japan

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.3c03663

Reference29 articles.

1. Norhalichondrin A: an antitumor polyether macrolide from a marine sponge

2. Halichondrins - antitumor polyether macrolides from a marine sponge

3. : Isolation and structure of halistatin 1 from the eastern Indian Ocean marine sponge Phakellia carteri

4. Antitumour polyether macrolides: Four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp.

5. Total synthesis of halichondrin B and norhalichondrin B

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Application of Ni/Zr-Mediated Ketone Coupling for the Scalable Synthesis of Homohalichondrin B;Organic Letters;2024-08-19

2. What Does It Take to Develop Structurally Complex Molecules by Total Synthesis? Rapid Process Development and GMP Manufacturing of E7130 Drug Substance for First-in-Human Clinical Study;Organic Process Research & Development;2024-04-15

3. Decagram-Scale Synthesis of an Anti-Cancer Drug Candidate;Synfacts;2024-03-13

4. Asymmetric Total Synthesis towards the Simplified Analogs of Antibiotic Elansolid A;Chinese Journal of Organic Chemistry;2024