Function-Oriented Studies Targeting Pectenotoxin 2: Synthesis of the GH-Ring System and a Structurally Simplified Macrolactone
Author:
Affiliation:
1. Department of Chemistry, Dartmouth College, Burke Laboratory, Hanover, New Hampshire 03755, United States
2. Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire 03755, United States
Funder
Dartmouth College
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.orglett.7b02435
Reference51 articles.
1. Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
2. Dinoflagellate polyether within the yessotoxin, pectenotoxin and okadaic acid toxin groups: Characterization, analysis and human health implications
3. Diarrhetic shellfish toxins
4. A Structural Basis for Regulation of Actin Polymerization by Pectenotoxins
5. Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors
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