Global Genome Mining Reveals a Cytochrome P450-Catalyzed Cyclization of Crownlike Cyclodipeptides with Neuroprotective Activity

Author:

Malit Jessie James Limlingan1ORCID,Liu Wenchao1,Cheng Aifang1,Saha Subhasish2,Liu Ling-Li13ORCID,Qian Pei-Yuan1

Affiliation:

1. Department of Ocean Science and Hong Kong Branch of Southern Marine Science and Engineering Guangdong Laboratory, The Hong Kong University of Science and Technology, Hong Kong, China

2. Laboratory of Algal Biotechnology-Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Opatovickýmlýn, Novohradská 237, 37981 Třeboň, Czech Republic

3. Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University 22 Xinong Road, Yangling 712100, Shaanxi, People’s Republic of China

Funder

Ministry of Science and Technology of the People's Republic of China

CRF grant from HKSAR government

Hong Kong Branch of Southern Marine Science and Engineering Guangdong Laboratory

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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