Modular Fragment Synthesis and Bioinformatic Analysis Propose a Revised Vancoresmycin Stereoconfiguration-Reference-Cited by-同舟云学术

Modular Fragment Synthesis and Bioinformatic Analysis Propose a Revised Vancoresmycin Stereoconfiguration

Published:2020-12-24 Issue:4 Volume:23 Page:1175-1180
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Spindler Stefanie¹,Wingen Lukas M.¹,Schönenbroicher Max¹,Seul Maximilian¹,Adamek Martina²,Essig Sebastian³,Kurz Michael⁴,Ziemert Nadine²^ORCID,Menche Dirk¹^ORCID

Affiliation:

1. Kekulé-Institut für Organische Chemie und Biochemie, Universität Bonn, Gerhard-Domagk-Str. 1, D-53121 Bonn, Germany

2. Interfaculty Institute of Microbiology and Infection Medicine, German Centre for Infection Research (DZIF), Partnersite Tuebingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany

3. Bayer AG, Aprather Weg 18a, D-42113 Wuppertal, Germany

4. Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, D-65926 Frankfurt am Main, Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c03957

Reference36 articles.

1. Isolation and structure elucidation of vancoresmycin—a new antibiotic from Amycolatopsis sp. ST 101170

2. Mode of Action and Heterologous Expression of the Natural Product Antibiotic Vancoresmycin

3. Synthesis of Tetramic Acid Fragments Derived from Vancoresmycin Showing Inhibitory Effects towards S. aureus

4. A Tylosin Ketoreductase Reveals How Chirality Is Determined in Polyketides

5. Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum

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