Raney-Co Mediated Reductive Cyclization of an α,β-Unsaturated Nitrile

Author:

Janey Jacob M.1,Orella Charles J.1,Njolito Eugenia1,Baxter Jenny M.1,Rosen Jonathan D.1,Palucki Michael1,Sidler Rick R.1,Li Wenjie1,Kowal Jason J.1,Davies Ian W.1

Affiliation:

1. Department of Process Research, Merck Research Laboratories, Merck and Co., Inc., Rahway, New Jersey 07065

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference15 articles.

1. Chemoselective Hydrogenation of ?,?-Unsaturated Nitriles

2. For a thorough review of nitrile reduction conditions, seeComprehensive Organic Synthesis,Vol. 8; Trost, B. M., Fleming, I., Eds.; Pergamon Press:  Oxford, U.K., 1991; pp 251−254.

3. Synthesis of L-canaline and .gamma.-functional 2-aminobutyric acid derivatives

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