Discovery of a Small-Molecule Probe for V-ATPase Function

Author:

Aldrich Leslie N.12,Kuo Szu-Yu23,Castoreno Adam B.2,Goel Gautam456,Kuballa Petric456,Rees Matthew G.2,Seashore-Ludlow Brinton A.2,Cheah Jaime H.2,Latorre Isabel J.2,Schreiber Stuart L.127,Shamji Alykhan F.2,Xavier Ramnik J.456

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

2. Center for the Science of Therapeutics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States

3. Department of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, Massachusetts 02138, United States

4. Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States

5. Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, United States

6. Program in Medical and Population Genetics, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States

7. Howard Hughes Medical Institute, Broad Institute, 415 Main Street, Cambridge, Massachusetts 02142, United States

Funder

National Cancer Institute

National Institute of Allergy and Infectious Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

Leona M. and Harry B. Helmsley Charitable Trust

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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