Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States-Reference-Cited by-同舟云学术

Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States

Published:2015-09-15 Issue:38 Volume:137 Page:12261-12268
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Qian Wenyuan¹,Wang Hao¹,Bartberger Michael D.¹

Affiliation:

1. Department of Medicinal Chemistry and ‡Department of Molecular Structure, Therapeutic Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States

Funder

Amgen

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.5b06189

Reference39 articles.

1. A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

2. Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

3. Click chemistry: function follows form

4. Click Chemistry: 1,2,3-Triazoles as Pharmacophores

5. 1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions

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