α-Arylation of Saturated Azacycles and N-Methylamines via Palladium(II)-Catalyzed C(sp3)–H Coupling-Reference-Cited by-同舟云学术

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α-Arylation of Saturated Azacycles and N-Methylamines via Palladium(II)-Catalyzed C(sp3)–H Coupling

Published:2015-09-10 Issue:37 Volume:137 Page:11876-11879
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Spangler Jillian E.¹,Kobayashi Yoshihisa²,Verma Pritha¹,Wang Dong-Hui¹,Yu Jin-Quan¹

Affiliation:

1. Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

2. Medicinal Chemistry, Eisai Product Creation Systems, Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba-shi, Ibaraki 300-2635, Japan

Funder

Eisai

The Scripps Research Institute

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.5b06740

Reference66 articles.

1. Direct sp3C–H bond activation adjacent to nitrogen in heterocycles

2. Direct α-Functionalization of Saturated Cyclic Amines

3. Complex Induced Proximity Effects: Enantioselective Syntheses Based on Asymmetric Deprotonations of N-Boc-pyrrolidines

4. Copper cyanide catalyzed palladium coupling of α-lithio amines and aryl iodides

5. Copper Cyanide-Catalyzed Palladium Coupling of N-tert-Butoxycarbonyl-Protected α-Lithio Amines with Aryl Iodides or Vinyl Iodides

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