Mechanistic Investigation of the Radical S-Adenosyl-l-methionine Enzyme DesII Using Fluorinated Analogues
Author:
Affiliation:
1. Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States
2. Division of Medicinal Chemistry, College of Pharmacy, University of Texas at Austin, Austin, Texas 78712, United States
Funder
National Institutes of Health
Welch Foundation
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.5b02545
Reference38 articles.
1. The Radical SAM Superfamily
2. Radical S-Adenosylmethionine Enzymes
3. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity
4. Biosynthesis of TDP-D-Desosamine: Identification of a Strategy for C4 Deoxygenation
5. Study of C-4 Deoxygenation in the Biosynthesis of Desosamine: Evidence Implicating a Novel Mechanism
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