Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling

Author:

Chou Danny Hung-Chieh1,Vetere Amedeo,Choudhary Amit2,Scully Stephen S.,Schenone Monica,Tang Alicia,Gomez Rachel,Burns Sean M.,Lundh Morten,Vital Tamara,Comer Eamon,Faloon Patrick W.,Dančík Vlado,Ciarlo Christie,Paulk Joshiawa,Dai Mingji,Reddy Clark,Sun Hanshi3,Young Matthew4,Donato Nicholas3,Jaffe Jacob,Clemons Paul A.,Palmer Michelle,Carr Steven A.,Schreiber Stuart L.1,Wagner Bridget K.

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

2. Society of Fellows, Harvard University, 78 Mount Auburn Street, Cambridge, Massachusetts 02138, United States

3. Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48103, United States

4. Department of Pharmacology, University of Michigan Medical School, 1150 W. Medical Center Drive, Ann Arbor, Michigan 48109, United States

Funder

National Human Genome Research Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Burroughs Wellcome Fund

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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