Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics-Reference-Cited by-同舟云学术

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Published:2005-09-23 Issue:21 Volume:48 Page:6544-6548
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Combs Andrew P.¹,Yue Eddy W.¹,Bower Michael¹,Ala Paul J.¹,Wayland Brian¹,Douty Brent¹,Takvorian Amy¹,Polam Padmaja¹,Wasserman Zelda¹,Zhu Wenyu¹,Crawley Matthew L.¹,Pruitt James¹,Sparks Richard¹,Glass Brian¹,Modi Dilip¹,McLaughlin Erin¹,Bostrom Lori¹,Li Mei¹,Galya Laurine¹,Blom Karl¹,Hillman Milton¹,Gonneville Lucie¹,Reid Brian G.¹,Wei Min¹,Becker-Pasha Mary¹,Klabe Ronald¹,Huber Reid¹,Li Yanlong¹,Hollis Gregory¹,Burn Timothy C.¹,Wynn Richard¹,Liu Phillip¹,Metcalf Brian¹

Affiliation:

1. Discovery Chemistry, Incyte Corporation, Experimental Station, E336/132A, Route 141 and Henry Clay Road, Wilmington, Delaware 19880

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0504555

Reference22 articles.

1. Protein Tyrosine Phosphatases and their Inhibitors

2. Protein tyrosine kinase inhibitors in cancer treatment

3. Increased Insulin Sensitivity and Obesity Resistance in Mice Lacking the Protein Tyrosine Phosphatase-1B Gene

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