Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening-Reference-Cited by-同舟云学术

Discovery of Potent Inhibitors of Soluble Epoxide Hydrolase by Combinatorial Library Design and Structure-Based Virtual Screening

Published:2011-02-08 Issue:5 Volume:54 Page:1211-1222
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xing Li¹²,McDonald Joseph J.¹,Kolodziej Steve A.¹,Kurumbail Ravi G.¹,Williams Jennifer M.¹,Warren Chad J.¹,O’Neal Janet M.¹,Skepner Jill E.¹,Roberds Steven L.¹

Affiliation:

1. Pfizer Global Research and Development, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, United States

2. Pfizer Global Research and Development, 200 CambridgePark Drive, Cambridge, Massachusetts 02140, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101382t

Reference39 articles.

1. Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology

2. Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

3. Epoxygenase Pathways of Arachidonic Acid Metabolism

4. Cytochrome P450 pathways of arachidonic acid metabolism

5. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)

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