1. 2nd Department of Medical Biochemistry, School of Medicine, Ehime University, Shigenobu-cho, Onsen-gun, Ehime 791-02, Japan
2. High Quality-Life Research Laboratories, Bio-Medical Division, Sumitomo Metal Industries, 3-5 Hikaridai, Seika-cho, Souraku-gun, Kyoto 619-02, Japan