1. School of Biosciences, University of Birmingham, Birmingham, B15 2TT, U.K., Department of Chemistry, Warwick University, Coventry, CV4 7AL, U.K., CRUK: Institute for Cancer Studies, University of Birmingham, Birmingham, U.K., School of Medicine, Institute of Life Science, Swansea University, Swansea SA2 8PP, U.K., School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, U.K., and Warwick Medical School, Warwick University, Coventry, CV4 7AL, U.K.