1. School of Health Sciences, Kanazawa University Faculty of Medicine, Kodatsuno, Kanazawa 920-0942, Japan, School of Mathematical and Physical Science, Graduate University for Advanced Studies, Myodaiji, Okazaki 444-8585, Japan, Sakai Womens Clinic, Itsukaichi, Iwate 028-4307, Japan, and Institute for Molecular Science, Okazaki National Research Institutes, Myodaiji, Okazaki 444-8585, Japan