Substituted 7-Amino-5-thio-thiazolo[4,5-d]pyrimidines as Potent and Selective Antagonists of the Fractalkine Receptor (CX3CR1)
Author:
Affiliation:
1. CNSP iMed Science Södertälje, AstraZeneca Research and Development, Innovative Medicines, SE-15185 Södertälje, Sweden
2. Pharmaceutical Development, AstraZeneca Research and Development, SE-15185 Södertälje, Sweden
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm3012273
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4. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
5. Recent Advances in the Design of Cathepsin S Inhibitors
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