Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine and 1-(3-Bromo-8-chloro-6,11- dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine-Reference-Cited by-同舟云学术

Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine and 1-(3-Bromo-8-chloro-6,11- dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine

Published:1998-02-19 Issue:6 Volume:41 Page:877-893
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mallams Alan K.¹,Rossman Randall R.¹,Doll Ronald J.¹,Girijavallabhan Viyyoor M.¹,Ganguly Ashit K.¹,Petrin Joanne¹,Wang Lynn¹,Patton Robert¹,Bishop W. Robert¹,Carr Donna M.¹,Kirschmeier Paul¹,Catino Joseph J.¹,Bryant Matthew S.¹,Chen Kwang-Jong¹,Korfmacher Walter A.¹,Nardo Cymbelene¹,Wang Shiyong¹,Nomeir Amin A.¹,Lin Chin-Chung¹,Li Zujun¹,Chen Jianping¹,Lee Suining¹,Dell Janet¹,Lipari Philip¹,Malkowski Michael¹,Yaremko Bodan¹,King Ivan¹,Liu Ming¹

Affiliation:

1. Antiinfectives and Tumor Biology Research, Schering-Plough Research Institute, Kenilworth, New Jersey 07033-0539

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970462w

Reference45 articles.

1. p21ras is modified by a farnesyl isoprenoid.

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