1. Department of Nutrition, University of North Carolina at Greensboro, North Carolina Research Campus, Kannapolis North Carolina 28081, Department of Colorectal Surgery, Cancer Hospital, and Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China, David H. Murdock Research Institute, Kannapolis, North Carolina 28081, and School of Pharmacy, and Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, P. R. China, 200240