Potent, Selective, and Orally Available Benzoisothiazolone Phosphomannose Isomerase Inhibitors as Probes for Congenital Disorder of Glycosylation Ia-Reference-Cited by-同舟云学术

Potent, Selective, and Orally Available Benzoisothiazolone Phosphomannose Isomerase Inhibitors as Probes for Congenital Disorder of Glycosylation Ia

Published:2011-05-03 Issue:10 Volume:54 Page:3661-3668
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Dahl Russell¹,Bravo Yalda¹,Sharma Vandana¹,Ichikawa Mie¹,Dhanya Raveendra-Panickar¹,Hedrick Michael¹,Brown Brock¹,Rascon Justin¹,Vicchiarelli Michael¹,Mangravita-Novo Arianna¹,Yang Li¹,Stonich Derek¹,Su Ying¹,Smith Layton H.¹,Sergienko Eduard¹,Freeze Hudson H.¹,Cosford Nicholas D. P.¹

Affiliation:

1. Apoptosis and Cell Death Research Program, ‡Conrad Prebys Center for Chemical Genomics, and §Sanford Children's Health Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101401a

Reference16 articles.

1. Towards a therapy for phosphomannomutase 2 deficiency, the defect in CDG-Ia patients

2. Congenital Disorders of Glycosylation: A Rapidly Expanding Disease Family

3. Genetic defects in the human glycome

4. Essentials of Glycosylation

5. Hydrophobic Man-1-P derivatives correct abnormal glycosylation in Type I congenital disorder of glycosylation fibroblasts

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