1. Chemical Process Research and Development, Chemistry Research and Discovery, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, and 360 Binney Street, Cambridge, Massachusetts 02142, Novasep, Site Eiffel-81, Boulevard de Moselle-BP50, 54340 Pompey, France, Chiral Technologies, 800 North Five Points Road, West Chester, Pennsylvania 19380, and Parc d’Innovation, Gonthier d’Andernach Boulevard, 67400 Illkrich-Cedex, France