1. Department of Pharmaceutical Sciences, University of Calabria, 87030 Arcavacata di Rende, Cosenza, Italy, Institute of General Pathology, Catholic University, Lgo F. vito, 1, 00168, Rome, Italy, Cosmetological Universitary Center, Catholic University, Lgo F. vito, 1, 00168 Rome, Italy, and Department of Cell Biology, University of Calabria 87030 Arcavacata di Rende, Cosenza, Italy