Asymmetric Total Synthesis of (−)-Leuconoxine via Chiral Phosphoric Acid Catalyzed Desymmetrization of a Prochiral Diester

Author:

Higuchi Kazuhiro1,Suzuki Shin1,Ueda Reeko1,Oshima Norifumi1,Kobayashi Emiko1,Tayu Masanori1,Kawasaki Tomomi1

Affiliation:

1. Meiji Pharmaceutical University, 2-522-1 Noshio Kiyose, Tokyo 204-8588, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference32 articles.

1. aVerpoorte, R.; van der Heijden, R.; Moreno, P. R. H.InThe Alkaloids: Chemistry and Pharmacology;Cordell, G. A., Ed.Academic Press:San Diego, 1997; Vol.49, p221.

2. bTakayama, H.; Sakai, S.I.InThe Alkaloids: Chemistry and Biology;Cordell, G. A., Ed.Academic Press:New York, 1998; Vol.50, p415.

3. cKam, T.S.; Lim, K.H.InThe Alkaloids: Chemistry and Biology;Cordell, G. A., Ed.Academic Press:The Netherlands, 2008; Vol.66, p1.

4. Indole alkaloids from leaves and stems of Leuconotis eugenifolius

5. First Total Synthesis of Hinckdentine A

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