Clotrimazole Scaffold as an Innovative Pharmacophore Towards Potent Antimalarial Agents: Design, Synthesis, and Biological and Structure–Activity Relationship Studies

Author:

Gemma Sandra1,Campiani Giuseppe1,Butini Stefania1,Kukreja Gagan1,Coccone Salvatore Sanna1,Joshi Bhupendra P.1,Persico Marco1,Nacci Vito1,Fiorini Isabella1,Novellino Ettore1,Fattorusso Ernesto1,Taglialatela-Scafati Orazio1,Savini Luisa1,Taramelli Donatella1,Basilico Nicoletta1,Parapini Silvia1,Morace Giulia1,Yardley Vanessa1,Croft Simon1,Coletta Massimiliano1,Marini Stefano1,Fattorusso Caterina1

Affiliation:

1. European Research Centre for Drug Discovery and Development and Dipartimento Farmaco Chimico Tecnologico, Università di Siena, via Aldo Moro, 53100 Siena, Italy, Dipartimento di Chimica delle Sostanze Naturali and Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, via D. Montesano 49, 80131 Napoli, Italy, Dipartimento di Sanità Pubblica-Microbiologia-Virologia, Universita′ di Milano, Via Pascal 36, 20133 Milano, Italy, Department of Infectious, Tropical Diseases,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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