Synthesis and Biological Evaluation of 4-(Aminomethyl)-1-hydroxypyrazole Analogues of Muscimol as γ-Aminobutyric AcidA Receptor Agonists-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 4-(Aminomethyl)-1-hydroxypyrazole Analogues of Muscimol as γ-Aminobutyric AcidA Receptor Agonists

Published:2013-01-23 Issue:3 Volume:56 Page:993-1006
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Petersen Jette G.¹,Bergmann Rikke¹,Møller Henriette A.¹,Jørgensen Charlotte G.¹²,Nielsen Birgitte¹,Kehler Jan³,Frydenvang Karla¹,Kristensen Jesper¹,Balle Thomas⁴,Jensen Anders A.¹,Kristiansen Uffe¹,Frølund Bente¹

Affiliation:

1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark

2. Department of Chemistry, University of Oxford, Mansfield Road, OX13TA, United Kingdom

3. H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark

4. Faculty of Pharmacy, The University of Sydney, Camperdown Campus, 2006 New South Wales, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301473k

Reference59 articles.

1. Glutamate- and GABA-based CNS therapeutics

2. GABAA Receptor Channel Pharmacology

3. Cys-Loop Neuroreceptors: Structure to the Rescue?

4. GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery?

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Classics in Chemical Neuroscience: Muscimol;ACS Chemical Neuroscience;2024-09-10

2. Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis;Communications Biology;2023-10-05

3. Recent Developments in the Practical Application of Novel Carboxylic Acid Bioisosteres;Current Medicinal Chemistry;2021-08-20

4. The Design and Application of Bioisosteres in Drug Design;Burger's Medicinal Chemistry and Drug Discovery;2021-04-28

5. Rational approaches for the design of various GABA modulators and their clinical progression;Molecular Diversity;2020-03-13