Differential Effects of Paclitaxel (Taxol) Analogs Modified at Positions C-2, C-7, and C-3' on Tubulin Polymerization and Polymer Stabilization: Identification of a Hyperactive Paclitaxel Derivative-Reference-Cited by-同舟云学术

Differential Effects of Paclitaxel (Taxol) Analogs Modified at Positions C-2, C-7, and C-3' on Tubulin Polymerization and Polymer Stabilization: Identification of a Hyperactive Paclitaxel Derivative

Published:1995-03-28 Issue:12 Volume:34 Page:3927-3934
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Grover Surinder,Rimoldi John M.,Molinero Anthony A.,Chaudhary Ashok G.,Kingston David G. I.,Hamel Ernest

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi00012a009

Reference40 articles.

1. Synthesis of 10-deacetoxytaxol and 10-deoxytaxotere

2. Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities

3. Taxol structure-activity relationships: synthesis and biological evaluation of 10-deoxytaxol

4. Synthesis of 7-deoxy- and 7,10-dideoxytaxol via radical intermediates

5. Serendipitous synthesis of a cyclopropane-containing taxol analog via anchimeric participation of an unactivated angular methyl group

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