Synthesis of Novel C4-Linked C2-Imidazole Ribonucleoside Phosphoramidite and Its Application to Probing the Catalytic Mechanism of a Ribozyme-Reference-Cited by-同舟云学术

Synthesis of Novel C4-Linked C2-Imidazole Ribonucleoside Phosphoramidite and Its Application to Probing the Catalytic Mechanism of a Ribozyme

Published:2009-02-16 Issue:6 Volume:74 Page:2350-2356
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Araki Lisa¹,Morita Keiji¹,Yamaguchi Maho¹,Zhao Zheng-yun¹,Wilson Timothy J.¹,Lilley David M. J.¹,Harusawa Shinya¹

Affiliation:

1. Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan, School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K., and Cancer Research UK Nucleic Acid Structure Research Group, MSI/WTB Complex, University of Dundee, Dundee DDI 5EH, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo802556s

Reference46 articles.

1. Nucleotide Analog Interference Mapping of the Hairpin Ribozyme: Implications for Secondary and Tertiary Structure Formation

2. Rescue of an Abasic Hairpin Ribozyme by Cationic Nucleobases

3. General acid catalysis by the hepatitis delta virus ribozyme

4. Model for General Acid−Base Catalysis by the Hammerhead Ribozyme: pH−Activity Relationships of G8 and G12 Variants at the Putative Active Site

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