Water Molecules Allow the Intramolecular Activation of the Thiamine Di-Phosphate Cofactor in Human Transketolase: Mechanistic Insights into a Famous Proposal-Reference-Cited by-同舟云学术

Water Molecules Allow the Intramolecular Activation of the Thiamine Di-Phosphate Cofactor in Human Transketolase: Mechanistic Insights into a Famous Proposal

Published:2021-03-18 Issue:7 Volume:11 Page:4136-4145
ISSN:2155-5435
Container-title:ACS Catalysis
language:en
Short-container-title:ACS Catal.

Author:

Medina Fabiola E.¹^ORCID,Prejanò Mario²

Affiliation:

1. Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Autopista Concepción-Talcahuano, Talcahuano 7100, Chile

2. Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm SE-10691, Sweden

Funder

Fondo Nacional de Desarrollo Cient?fico y Tecnol?gico

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscatal.0c05414

Reference76 articles.

1. A new perspective on thiamine catalysis

2. Domain Relationships in Thiamine Diphosphate-Dependent Enzymes

3. The importance of thiamine (vitamin B1) in plant health: From crop yield to biofortification

4. How Thiamine Diphosphate Is Activated in Enzymes

5. Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. On the Mechanism of the Lysosomal Enzyme Iduronate‐2‐sulfatase. A Multiscale Approach;ChemCatChem;2024-04-26

2. Dynamic Protonation States Underlie Carbene Formation in ThDP-Dependent Enzymes: A Theoretical Study;The Journal of Physical Chemistry B;2023-09-25

3. Frontiers in the enzymology of thiamin diphosphate-dependent enzymes;Current Opinion in Structural Biology;2022-10

4. QM/MM Study of a VIM-1 Metallo-β-Lactamase Enzyme: The Catalytic Reaction Mechanism;ACS Catalysis;2021-12-09

5. QM/MM Study of Human Transketolase: Thiamine Diphosphate Activation Mechanism and Complete Catalytic Cycle;Journal of Chemical Information and Modeling;2021-06-23