Local Structural Dynamics at the Metal-Centered Catalytic Site of Polymerases is Critical for Fidelity
Author:
Affiliation:
1. Laboratory of Molecular Modelling & Drug Discovery, Istituto Italiano di Tecnologia, Via Morego 30, Genoa 16163, Italy
Funder
Ministero dell???Istruzione, dell???Universit?? e della Ricerca
Associazione Italiana per la Ricerca sul Cancro
Publisher
American Chemical Society (ACS)
Subject
Catalysis,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c03840
Reference101 articles.
1. How DNA polymerases catalyse replication and repair with contrasting fidelity
2. The Catalytic Mechanism of DNA and RNA Polymerases
3. DNA Replication Fidelity
4. DNA Polymerases as Therapeutic Targets
5. Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics
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