Engineering P450 Monooxygenases for Highly Regioselective and Active p-Hydroxylation of m-Alkylphenols

Author:

Li Ren-Jie12,Tian Kaiyuan1,Li Xirui1,Gaikaiwari Anand Raghavendra1,Li Zhi12ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore

2. Synthetic Biology for Clinical and Technological Innovation (SynCTI), National University of Singapore, 28 Medical Drive, Singapore 117456, Singapore

Funder

National Research Foundation Singapore

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

Reference101 articles.

1. Cytochrome P450 Monooxygenases in Biotechnology and Synthetic Biology

2. aNishimura, S., Kotani, T. Method for producing benzyl alcohol compound. Ishihara Sangyo Kaisha Ltd, Patent No. JP2003055281-A, 2003.

3. bKobayashi, K., Ota, K., Shinei, Y., Katano, K. Benzyl alcohol derivative having platelet aggregation-inhibiting action. Meiji Seika Kaisha Ltd, Patent No. JP11279174-A, 1999.

4. Benzylic hydroxylation of aromatic compounds by P450 BM3

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