Molecular Insights into the Regioselectivity of the Fe(II)/2-Ketoglutarate-Dependent Dioxygenase-Catalyzed C–H Hydroxylation of Amino Acids

Author:

Wu Lunjie1ORCID,An Jianhong12,Jing Xiaoran1,Chen Chun-Chi3,Dai Longhai3,Xu Yan1,Liu Weidong4ORCID,Guo Rey-Ting3ORCID,Nie Yao15ORCID

Affiliation:

1. Laboratory of Brewing Microbiology and Applied Enzymology, School of Biotechnology and Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, Jiangsu 214122, China

2. School of Ophthalmology and Optometry, and Eye Hospital, Wenzhou Medical University, State Key Laboratory of Optometry, Ophthalmology and Vision Science, Wenzhou, Zhejiang 325000, China

3. State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Hubei Key Laboratory of Industrial Biotechnology, School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China

4. Industrial Enzymes National Engineering Laboratory, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China

5. Suqian Industrial Technology Research Institute of Jiangnan University, Suqian, Jiangsu 223814, China

Funder

Ministry of Science and Technology of the People's Republic of China

Government of Jiangsu Province

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Higher Education Discipline Innovation Project

Top-notch Academic Programs Project of Jiangsu Higher Education Institutions

High-end Foreign Experts Recruitment Program

Postgraduate Research and Practice Innovation Program of Jiangsu Province

National First-Class Discipline Program of Light Industry Technology and Engineering

Key Laboratory of Enzymes of Suqian

Publisher

American Chemical Society (ACS)

Subject

Catalysis,General Chemistry

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